SERENITY will be organised through 6 work packages over a five-year timescale

OUTPUT WP1: UNDERSTANDING CURRENT PRACTICE AND THE COMPLEXITY OF DECISION-MAKING IN END-OF-LIFE CARE

Flash mob study

The pre-registration for the flash mob study was closed after 467 pre-registrations.
The survey was launched on 4 July 2023 and closed on July 11 2023. The final numbers of completed surveys and partially completed surveys were 180 and 28, respectively

Achievements

Study initiation packages for epidemiological studies, including protocol with complete statistical plan.
Study initiation packages for realist review, including registration on PROSPERO.
Report on findings of the realist review on PROSPERO.

 

OUTPUT WP 2: Epidemiological studies

Achievements

Report on findings of the Danish study submitted.
Report on findings of the Dutch study submitted.

Early findings from the Realist Review

Poster presentation by Gazme Keser et al.
Towards cancer patient empowerment for optimal use of antithrombotic therapy at the end of life (SERENITY): A realist review of how deprescribing interventions can improve shared decision making for cancer patients in the last year of life.

 

Output WP3: Qualitative research

Achievements

Midterm recruitment report of qualitative studies submitted.
For Work Package 3 the first interviews have started.
The pre-registration for the Physician Survey has been opened.

Output WP4: Delphi process
Output WP5: Development and testing of the Shared Decision Support Tool
Output WP6: Cluster-randomized controlled trial

Publications

Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool.
Goedegebuur J et al. Thromb Res. 2023 Aug: 228:54-60.
DOI: 10.1016/j.thromres.2023.05.008

Upcoming Consortium Meetings

02-04-2024, 19-04-2024, 27-09-2024

Past Consortium Meetings

27-01-2023, 21-04-2023, 01-09-2023

Timeline serenity project (duration 60 months)

month 0

month 60

  • FAIR data management and stewardship
  • Phase 1 | WP1: Realist review and Flash mob study
  • Phase 1 | WP2: Epidemiologic studies
  • Phase 1 | WP3: Qualitative studies
  • Phase 2 | WP4: Delphi
  • Phase 2 | WP5: Tool development, design and testing
  • Phase 3 | WP6: RCT
  • Phase 3 | WP7: Dissemination
  • WP8: Project Management
  • Public engagement